Autofilter error: the object invoked has disconnected from its clients

Well it seems that the problem was twofold, one that the Criteria needed to be a string and it was getting an integer back and secondly Operator:=xlFilterValues being placed after instructions with only a single variable was looked poorly upon by the excel gods.

In my case at least, this isn't a problem anymore. Hopefully this information helps someone else in the future!

Revised code:

Option Explicit

Private Sub CommandButton49_Click()
'
Dim Wsdnd As Worksheet

Set Wsdnd = Sheets("DO NOT DELETE")

Dim A0, A1, A2, A3, A4, A5, A6, A7, A8, A9, A10, ... (more variables) As Range

A4 = Wsdnd.Range("BD4").Value
A5 = Wsdnd.Range("BD5").Value
A6 = Wsdnd.Range("BD6").Value
A7 = Wsdnd.Range("BD7").Value
A8 = Wsdnd.Range("BD8").Value
... (More variables)
'
    Wsdnd.Range("BC3:BE50").Calculate          'Refreshing "Category", "Apply All Data", "Match Lookup Value" Lists on DO NOT DELETE sheet
        Application.Calculation = xlManual      'Restarts manual calculations only for workbook speed
'
'Filter #4
    If Not IsEmpty(A6) Then
        Sheets("Database").Range("B$24:BL$71499").AutoFilter Field:=WorksheetFunction.Match(Sheets("DO NOT DELETE").Range("BE6"), _
                Worksheets("Database").Range("B23:BL23"), 0), Criteria1:=A6
            Else
    End If
'
'Filter #5
    If Not IsEmpty(A7) Then
        Sheets("Database").Range("B$24:BL$71499").AutoFilter Field:=WorksheetFunction.Match(Sheets("DO NOT DELETE").Range("BE7"), _
                Worksheets("Database").Range("B23:BL23"), 0), Criteria1:=A7
            Else
    End If
'
'Filter #6
    If Not IsEmpty(A8) Then
        Sheets("Database").Range("B$24:BL$71499").AutoFilter Field:=WorksheetFunction.Match(Sheets("DO NOT DELETE").Range("BE8"), _
                Worksheets("Database").Range("B23:BL23"), 0), Criteria1:=A8
            Else
    End If

Filter a Worksheet

Option Explicit

Private Sub CommandButton49_Click()
    FilterWorksheet
End Sub

Sub FilterWorksheet()
    Const ProcName As String = "FilterWorksheet"
    On Error GoTo ClearError
 
    Const sName As String = "DO NOT DELETE"
    Const srgAddress As String = "BC3:BE50" ' ?
    Const srrgAddress As String = "BD4:BD10" ' resize
    Const scOffset As Long = 1 ' ('BE4:BE10')
    
    Const dName As String = "Database"
    Const drgAddress As String = "B23:BL71499"
     
    Dim wb As Workbook: Set wb = ThisWorkbook ' workbook containing this code

    Dim sws As Worksheet: Set sws = wb.Worksheets(sName)
    Dim srg As Range: Set srg = sws.Range(srgAddress)
    Dim srrg As Range: Set srrg = sws.Range(srrgAddress)
    
    Dim dws As Worksheet: Set dws = wb.Worksheets(dName)
    If dws.AutoFilterMode Then dws.AutoFilterMode = False
    Dim drg As Range: Set drg = dws.Range(drgAddress)
    Dim dhrg As Range: Set dhrg = drg.Rows(1)

    With Application
        .ScreenUpdating = False
        .Calculation = xlCalculationManual
        .EnableEvents = False
    End With
    
    srg.Calculate 'Refreshing "Category", "Apply All Data", "Match Lookup Value"

    Dim sCell As Range
    Dim sValue As Variant
    Dim dField As Variant
        
    For Each sCell In srrg.Cells
        sValue = sCell.Value
        If Not IsError(sValue) Then
            If Len(CStr(sValue)) > 0 Then
                dField = Application _
                    .Match(sCell.Offset(, scOffset).Value, dhrg, 0)
                If IsNumeric(dField) Then
                    drg.AutoFilter Field:=dField, Criteria1:=sValue
                End If
            End If
        End If
    Next sCell
    
SafeExit:
    
    With Application
        .EnableEvents = True
        .Calculation = xlCalculationAutomatic
        .ScreenUpdating = True
    End With
    
    Exit Sub
ClearError:
    Debug.Print "'" & ProcName & "' Run-time error '" _
        & Err.Number & "':" & vbLf & "    " & Err.Description
    Resume SafeExit
End Sub