Oracle RegEx in a Cast Procedure

I have a Cast Procedure for a table with "raw" data. Any time a record comes from any of our locations into the raw table, my procedure "cleans" the data and loads it into a new table. The original raw table is all varchars and my procedure converts date and number fields to the proper data types. From the clean table, a Java program selects any new records on a daily basis and FTPs them off in a file to another dept. Have just learned that a few of the fields accept input from users and on a rare occasion, someone uses a pipe in what they input. A pipe symbol happens to be the delimiter that the other dept is using and whenever a pipe shows up in the middle of a field, it throws a wrench on their end.

I've never used REGEX or REGEXP_REPLACE in Oracle before. There are only three fields where the users can input data - MISTINTCOMMENT, PALETTE, COLORID. How do I use REGEX or REGEXP_REPLACE to replace any pipes with a space? Do I want to do it on each field? Or is this something I should "wrap around" the entire statement (in case there's a field I missed where someone might be able to input a pipe)?

Here is the portion of the procedure where the Values are cleaned and inserted into new table. How to best use RegEx with this?

VALUES (CASE 
        WHEN THECOSTCENTER IS NOT NULL
            THEN THECOSTCENTER
            ELSE (SUBSTR(TRIM(THESENDING_QMGR), -6))
            END, 
        CASE    
        WHEN THESTORENBR = '0' AND (SUBSTR(THESENDING_QMGR, 1, 5) = 'PDPOS')
            THEN TO_NUMBER(SUBSTR(THESENDING_QMGR, 8, 4))
        WHEN THESTORENBR = '0' AND (SUBSTR(THESENDING_QMGR, 1, 8) = 'PROD_POS')
            THEN TO_NUMBER(SUBSTR(THESENDING_QMGR, 9, 4))
            ELSE TO_NUMBER(NVL(THESTORENBR,'0')) 
        END, 
        TO_NUMBER(NVL(THECONTROLNBR,'0')), TO_NUMBER(NVL(THELINENBR,'0')), THESALESNBR, TO_NUMBER(NVL(THEQTYMISTINT,'0')), THEREASONCODE, THEMISTINTCOMMENT, 
        THESIZECODE, THETINTERMODEL, THETINTERSERIALNBR, TO_NUMBER(NVL(THEEMPNBR,'0')), TO_DATE(THETRANDATE,'YYYY-MM-DD'), THETRANTIME, THECDSADLFLD, 
        THEPRODNBR, THEPALETTE, THECOLORID, TO_DATE(THEINITTRANDATE,'YYYY-MM-DD'), TO_NUMBER(NVL(THEGALLONSMISTINTED,'0'),'999999999.99'), THEUPDATEEMPNBR, 
        TO_DATE(THEUPDATETRANDATE,'YYYY-MM-DD'), TO_NUMBER(NVL(THEGALLONS,'0'),'999999999.99'), THEFORMSOURCE, THEUPDATETRANTIME, THESOURCEIND, 
        TO_DATE(THECANCELDATE,'YYYY-MM-DD'), THECOLORTYPE, TO_NUMBER(NVL(THECANCELEMPNBR,'0')), TO_BOOLEAN(THENEEDEXTRACTED), TO_BOOLEAN(THEMISTINTMQXTR), 
        THEDATASOURCE, THETRANGUID, TO_NUMBER(NVL(THETERMNBR,'0')), TO_NUMBER(NVL(THETRANNBR,'0')), TO_NUMBER(NVL(THETRANID,'0')), THEID, THETINTABLESALESNBR,
        TO_NUMBER(NVL(THERETURNQTY,'0')), THECREATED_TS, THEXMIT_GUID, THESENDING_QMGR, THEMSG_ID, THEPUT_TS, 
        THEBROKER_NAME, THECHECKSUM);