You can use
\bt(?:[a-z]*[a-df-z])?\b
\bt[a-z]*\b(?<!e)
Just for completeness, here is a regex to match any word starting with a Cyrillic т and not ending with a Cyrillic е:
\bт[^\W\d_]*\b(?<!е)
See the regex demo #1, regex demo #2 and a Cyrillic regex demo.
If you need a case insensitive matching, add re.I:
re.findall(r'\bt(?:[a-z]*[a-df-z])?\b', text, re.I)
And a note on word boundaries: if the words can be glued to _ or digits, use letter boundaries rather than word boundaries:
r'(?<![a-z])t(?:[a-z]*[a-df-z])?(?![a-z])'
r'(?<![^\W\d_])т[^\W\d_]*(?![^\W\d_])(?<!е)' # Unicode letter boundaries
Regex details
\b - word boundary (start of string or a position immediately after a char other than a digit, letter, underscore)
(?<![a-z]) ((?<![^\W\d_]) is a Unicode aware equivalent) - a negative lookbehind that matches a location that is not immediately preceded with a letter
t - a t letter
(?:[a-z]*[a-df-z])? - an optional non-capturing group matching 0 or more letters and then a letter other than e
\b - word boundary
(?![a-z]) ((?![^\W\d_]) is a Unicode aware equivalent) - a negative lookahead that matches a location that is not immediately followed with a letter.
Also,
\bt[a-z]*\b(?<!e) matches a word boundary, t, any zero or more lowercase ASCII letters (any ASCII letters with re.I), then a word boundary marks the end of a word and the negative lookbehind (?<!e) fails the match if there is e at the end of the word
[^\W\d_]* - matches zero or more more Unicode letters.
See a Python demo:
import re
text = r't, train => main,teene!'
cyr_text = r'таня тане работе'
print( re.findall(r'\bt(?:[a-z]*[a-df-z])?\b', text, re.I) )
# => ['t', 'train']
print( re.findall(r'\bt[a-z]*\b(?<!e)', text, re.I) )
# => ['t', 'train']
print( re.findall(r'\bт[^\W\d_]*\b(?<!е)', cyr_text, re.I) )
# => ['таня']
print( re.findall(r'(?<![^\W\d_])т[^\W\d_]*(?![^\W\d_])(?<!е)', cyr_text, re.I) )
# => ['таня']