The simplest way to avoid var with multiple conditions is to use temporary values
val a1 = 2
val a2 = if (condition) a1*3 else a1
val a3 = if (condition2) a2*6 else a2
val a = if (condition3) a3*8 else a3
val b = a * 2/*someOperation*/
In the real code you would give a1, a2, and a3 meaningful names to describe the result of each stage of processing.
If you are bothered about having these extra values in scope, put it in a block:
val a = {
val a1 = 2
val a2 = if (condition) a1*3 else a1
val a3 = if (condition2) a2*6 else a2
if (condition3) a3*8 else a3
}
Update
If you want a more functional approach, collect the conditions and modifications together and apply them in turn, like this:
val mods: List[(Boolean, Int=>Int)] = List(
(condition, _*3),
(condition2, _*6),
(condition3, _*8)
)
val a = mods.foldLeft(2){ case (a,(cond, mod)) => if (cond) mod(a) else a }
This is really only appropriate when either the conditions or the modifications are more complex, and keeping them together makes the code clearer.