How do I make a personal call using Twilio?

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I've read the Twilio phone call tutorial here: https://www.fullstackpython.com/blog/make-phone-calls-python.html

Unlike the Twilio tutorial, which it does call my phone, but It only plays MP3 or a AI voice. I want to be able to make conversation. It there a way to connect my computer's microphone and speak to talk to my own phone using Twilio API? I've been search all over the internet and couldn't find a way. Please help.

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