Remove/replace special characters in column values?

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I have a table column containing values which I would like to remove all the hyphens from. The values may contain more than one hyphen and vary in length.

Example: for all values I would like to replace 123 - ABCD - efghi with 123ABCDefghi.

What is the easiest way to remove all hyphens & update all column values in the table?

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