How many decision variables can be solved for Mixed Integer Programming?

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I have a Mixed Integer Programming problem(binary integer variables), how many variables can I solve, i.e, upper limit and what would be time taken?

The problem would have a utmost 5 constraints and a minimisation cost function, but variables are in the form of a matrix of m*n. So, the question is what could be the max values of m and n, also the time it would take to finish the computation?

Using standard software/libraries like COIN CBC, GLPK, CPLEX, GUROBI.

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