Azure does not override application settings

In my Azure App Service I want to update application settings, but after publish from VS the keys doesn't override values from local Web.config

In Azure it looks like:

In the result my web.config on azure contains values from local settings

  <connectionStrings>
    <add name="MainConnectionString" connectionString="ConnectionStringToReplaceByAzure" providerName="System.Data.SqlClient" />
  </connectionStrings>
  <appSettings>
    <add key="MS_SigningKey" value="Overridden by portal settings" />
  </appSettings>