What does DOM loadtime in the page load timings represent?

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This is how the typical loadtime of one of my page splits into :-

Domain Lookup     0            0 %
Connect           134          .3%
Request         19658          40%
Response          134          .3%
DOM             28808          58%
Interactive         1           -
Content Loaded   1427           -
Load Event        645           1%

These values are as per shown by chrome extension Page Rank Status. Now clearly the request and DOM part are the largest time consuming parts. Can anyone explain me what do Request, Response, DOM, Interactive, Load Event exactly corresponds to ? THis would help me in optimizing my website and reduce the overall page load time.

Thanks !

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