How can I enable App Sandboxing for specific build configuration

I'm developing a Mac app, and preparing submit it to Mac AppStore.

I want distribute it on my website too, at the same time.

Since I use Sparkle framework to manage updates for the version outside AppStore, the app can NOT be sandboxed.

I know I can done this with multiple build targets, but keey two targets in sync is too heavy, since the only different is sandbox or not.

So I create a build configuration, and my configurations list like this:

• Debug : for development, Sandbox Disabled
• Release : for distributing outside Mac AppStore, Sandbox Disabled
• MacAppStore : for distributing to Mac AppStore, Sandbox Enabled

How can I enable Sandbox only for MacAppStore configuration?