Updating a submatrix of Mat in OpenCV

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I am working with OpenCV and C++. I have a matrix X like this

Mat X = Mat::zeros(13,6,CV_32FC1);

and I want to update just a submatrix 4x3 of it, but I have doubts on how to access that matrix in an efficient way.

Mat mat43= Mat::eye(4,3,CV_32FC1);  //this is a submatrix at position (4,4)

Do I need to change element by element?

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