I have to do some find and replace tasks on a rather big file , about 47 GB in size .
Does anybody know how to do this ? I tried using services like TextCrawler , EditpadLite and more but nothing supports this large a file .
I'm assuming this can be done via the commandline .
Do you have an idea how this can be accomplished ?
I solved the problem usig, before, split to reduce the large file in smalls with 100 MB each.
I used
sed 's/[nN]//g' oldfile.fasta > newfile.fasta
to replace all the instances of n's in my 7Gb file.
If I omitted the > newfile.fasta aspect it took ages as it scrolled up the screen showing me every line of the file.
With the > newfile it ran it in a matter of seconds on an ubuntu server