What does |= (single pipe equal) and &=(single ampersand equal) mean

In below lines:

//Folder.Attributes = FileAttributes.Directory | FileAttributes.Hidden | FileAttributes.System | FileAttributes.ReadOnly;
Folder.Attributes |= FileAttributes.Directory | FileAttributes.Hidden | FileAttributes.System | FileAttributes.ReadOnly;


Folder.Attributes |= ~FileAttributes.System;
Folder.Attributes &= ~FileAttributes.System;

What does |= (single pipe equal) and &= (single ampersand equal) mean in C#?

I want to remove system attribute with keeping the others...