How to change a Pseudo-class style through JavaScript?

This example is, for a matter of simplicity, just an illustration of what I need to do. Say, I have an element, which style is set in a CSS. The style is set for the element as well as for a Pseudo-class, say element:hover. I can override the style for the element with the following JavaScript: element.style.setProperty('property-name', 'new value', ''). How can I change the Pseudo-class's style through JavaScript?

Thank you.

<html>
<head>
      <style type='text/css'>
             #myBtn {
                background-color: red;
             }
             #myBtn:hover {
                background-color: blue;
             }
      </style>
</head>
<body>
      <button id='myBtn'>Colored button</button>

      <button onclick="ChangeColor();">Script button</button>

      <script type="application/x-javascript">
              function ChangeColor() {
                 var Btn = document.getElementById('myBtn');
                 Btn.style.setProperty('background-color', 'green', '');
              };
      </script>
</body>
</html>