Subsetting data in Python

I want to use the equivalent of the subset command in R for some Python code I am writing.

Here is my data:

col1    col2    col3    col4    col5
100002  2006    1.1 0.01    6352
100002  2006    1.2 0.84    304518
100002  2006    2   1.52    148219
100002  2007    1.1 0.01    6292
10002   2006    1.1 0.01    5968
10002   2006    1.2 0.25    104318
10002   2007    1.1 0.01    6800
10002   2007    4   2.03    25446
10002   2008    1.1 0.01    6408

I want to subset the data based on contents of col1 and col2. (The unique values in col1 are 100002 and 10002, and in col2 are 2006,2007 and 2008.)

This can be done in R using the subset command, is there anything similar in Python?