Update an UpdatePanel manually using JavaScript or jQuery

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Is it possible to update an UpdatePanel manually using JavaScript or jQuery?

What I have is a TextBox at the top of my page. When a user leaves that TextBox I want to run some server code (it will add a record to my database) then at the bottom of the page I have an UpdatePanel which will get refreshed. The UpdatePanel has a GridView which will have an entry for the record added)

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