Is it a bad idea to put development shortcuts in #if DEBUG blocks?

In a few places in our code we use #if DEBUG blocks to simplify development. Things like:

#if DEBUG
   serverIP = localhost;
#else
   serverIP = GetSetting()
#endif

private bool isLicensed()

#if DEBUG
   return true;
#endif

return CheckSetting()

There are also a few places where we make cosmetic changes like this:

#if DEBUG
   background = humorousImage.jpg
#else
   background = standardColor
#endif

Is it dangerous to depend on #if debug to make development easier? If it is, what is a valid use of #if debug?