What is the last event to fire when loading a new WPF/C# window?

I am trying to load a preferences window for my application and I would like the apply button to initially be disabled, then when a preference is updated, the apply button gets enabled again. I have some controls data bound to a preferences object and what happens is that after the window loads, the combobox events get triggered. Is there any event that is guaranteed to happen dead last after everything is stable?

Here is what my code looks like (the apply button is always enabled after the window loads):

private void Window_Loaded(object sender, RoutedEventArgs e)
{
    _preferencesData = new PreferencesDataContext();
    LayoutRoot.DataContext = _preferencesData;
    ButtonApply.IsEnabled = false;
}

private void ComboBox_SelectionChanged(object sender, System.Windows.Controls.SelectionChangedEventArgs e)
{
    ButtonApply.IsEnabled = true;
}

Is it also interesting to note that this only happens with textboxes and comboboxes, not checkboxes or radiobuttons.