Parameterized queries with psycopg2 / Python DB-API and PostgreSQL

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What's the best way to make psycopg2 pass parameterized queries to PostgreSQL? I don't want to write my own escpaing mechanisms or adapters and the psycopg2 source code and examples are difficult to read in a web browser.

If I need to switch to something like PyGreSQL or another python pg adapter, that's fine with me. I just want simple parameterization.

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