As Knuth said,
We should forget about small efficiencies, say about 97% of the time: premature optimization is the root of all evil.
This is something which often comes up in Stack Overflow answers to questions like "which is the most efficient loop mechanism", "SQL optimisation techniques?" (and so on). The standard answer to these optimisation-tips questions is to profile your code and see if it's a problem first, and if it's not, then therefore your new technique is unneeded.
My question is, if a particular technique is different but not particularly obscure or obfuscated, can that really be considered a premature optimisation?
Here's a related article by Randall Hyde called The Fallacy of Premature Optimization.