During iOS runtime can we write/modify data in __DATA of mach-o file?

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As far as I've known that mach-o would be loaded into memory during iOS app launching and dyld would link all the necessary libs to the mach-o and combine them to address all the symbols.

After that runtime is on stage, so my question is can we access the mach-o and write/modify at least __DATA section, such as I would like to store some info onto the __DATA section?

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