how to add specific data from rows into a new column?

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If I have a dataset that looks something like this

#of passengers Route number of flights cost per fl revenue from each fl profit from each fl
194 RSW-CLE 14 19409.50 74302 54892.50
110 RSW-CMH 12 19409.50 53350 33940
182 ATL-LAX 11 18537.40 44226 25688.60
134 ORD-LAX 8 12574.45 78413 151446.60

First I want to add the total cost per fl, total profit per fl and then I want to show the routes with the most profit in a summary file. How do I go about doing that?

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