I want to run QC on my sce object but the sparse matrix is too large for R to process that. This is the error I got:
Error in asMethod(object) : Cholmod error 'problem too large' at file ../Core/cholmod_dense.c, line 102e
My matrix is [17284 x 151789] large and this is the code I want to run on it.
sce<-getUMAP(inSCE = sce, useAssay = "counts", logNorm = TRUE, reducedDimName = "QC_UMAP", seed = 12345)
I know it is the memory problem but by increasing the RAM, it doesn't solve the issue. So, I am thinking to run it in chunks but I need more help for that part. Thank you in advance!