How do you filter one field using multiple values in ListAPIView in Django REST framework?

You can use the django-filter package's DjangoFilterBackend for that:

from django_filters import DjangoFilterBackend

class profile_view(generics.ListAPIView):
    queryset = ModelName.objects.all()
    serializer_class = SerializerName
    filter_backends = [DjangoFilterBackend]
    filter_fields = {
        'status': ["in", "exact"] # icontains ,exact, gte, lte, in
         # if you want to add more fields, you can
    }

then you can filter data by ?status__in=active, pending or status=active.

Yes, you can use DjangoDefaultFilterBackend like that:

from django_filters import DjangoFilterBackend
class YourListAPI(generics.ListAPIView):
    queryset = YourModel.objects.all()
    serializer_class = YourSerializer
    filter_backends = [DjangoFilterBackend]
    filterset_fields = ['status']

You can find more detail abouth drf-filtering

If you want to use filter multiple values for same field , there is a good answer here