I work in several groups, each of which has its own tab/indentation/spacing standards in C.
I work with all sorts of open source, all at the same time. It's not practical to be creating separate .vimrc files and reconfiguring the formatting standards. More than a decade ago, I finally got tired of dealing with the editor configuration and wrote a program called autotab to handle it.
When autotab is set up with Vim suggested, each time you load a file into Vim, autotab is invoked on it, and the Vim settings output autotab are passed to a :set command.
autotab reads several thousand lines from the file, analyzes them and determines the settings for the expandtab, tabstop and shiftwidth parameters.
It figures out whether the file uses hard tabs or just spaces for indentation, and it figures out the indentation size. If the file is indented with tabs, it figures out the right tab size, based on rendering the file sample using various tab sizes and judging it according to heuristics like line-over-line alignment of internal elements.
It works well enough that I stopped tweaking the algorithm years ago. If it gets confused, it's almost always because the file has formatting issues, such as the use of multiple conventions at the same time.
It is also "agnostic" of the file type and works well with a variety of different languages. I use it not only over C, but shell scripts, Lisp, Makefiles, HTML, and what have you.
Note that it doesn't handle other parameters of formatting that may be project-specific, like for instance, in C files, whether case labels in a switch statement are indented or not, or whether wrapped function argument lists are simply indented, or aligned to the opening parenthesis of the argument list. Vim does have settings for that sort of thing, and so the program could be plausibly extended to analyze the style and output those parameters.