My Django project is going to be backed by a large database with several hundred thousand entries, and will need to support searching (I'll probably end up using djangosearch or a similar project.)
Which database backend is best suited to my project and why? Can you recommend any good resources for further reading?
As someone who recently switched a project from MySQL to Postgresql I don't regret the switch.
The main difference, from a Django point of view, is more rigorous constraint checking in Postgresql, which is a good thing, and also it's a bit more tedious to do manual schema changes (aka migrations).
There are probably 6 or so Django database migration applications out there and at least one doesn't support Postgresql. I don't consider this a disadvantage though because you can use one of the others or do them manually (which is what I prefer atm).
Full text search might be better supported for MySQL. MySQL has built-in full text search supported from within Django but it's pretty useless (no word stemming, phrase searching, etc.). I've used django-sphinx as a better option for full text searching in MySQL.
Full text searching is built-in with Postgresql 8.3 (earlier versions need TSearch module). Here's a good instructional blog post: Full-text searching in Django with PostgreSQL and tsearch2
large database with several hundred thousand entries,
This is not large database, it's very small one.
I'd choose PostgreSQL, because it has a lot more features. Most significant it this case: in PostgreSQL you can use Python as procedural language.
Go with whichever you're more familiar with. MySQL vs PostgreSQL is an endless war. Both of them are excellent database engines and both are being used by major sites. It really doesn't matter in practice.
Having gone down the road of MySQL because I was familiar with it (and struggling to find a proper installer and a quick test of the slow web "workbench" interface of postgreSQL put me off), at the end of the project, after a few months after deployment, while looking into back up options, I see you have to pay for MySQL's enterprise back up features. Gotcha right at the very end.
With MySql I had to write some ugly monster raw SQL queries in Django because no select distinct per group for retrieving the latest per group query. Also looking at postgreSQL's full-text search and wishing I had used postgresSQL.
I recommend PostgreSQL even if you are familiar with MySQL, but your mileage may vary.
UPDATE: DBeaver is a great equivalent of MySql Workbench gui tool but works with PostgreSQL very nicely (and many others as its a universal DB tool).
Will this application be hosted on your own servers or by a hosting company? Make sure that if you are using a hosting company, they support the database of choice.
There is a major licensing difference between the two db that will affect you if you ever intend to distribute code using the db. MySQL's client libraries are GPL and PostegreSQL's is under a BSD like license which might be easier to work with.
